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LCL-161

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LCL-161 Basic information

Product Name:
LCL-161
Synonyms:
  • LCL-161
  • N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-MethylalaninaMide
  • (2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide
  • (S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)
  • N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-(2S)-propanamide
  • (2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide LCL 161
  • LCL161, 98%, inhibitor of Apoptosis Protein (IAP) family of proteins
  • CS-987
CAS:
1005342-46-0
MF:
C26H33FN4O3S
MW:
500.63
Product Categories:
  • Inhibitors
Mol File:
1005342-46-0.mol
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LCL-161 Chemical Properties

Boiling point:
713.7±60.0 °C(Predicted)
Density 
1.245±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form 
solid
pka
14.25±0.46(Predicted)
color 
White to yellow
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Safety Information

RIDADR 
3077
HS Code 
29341000
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LCL-161 Usage And Synthesis

Description

LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins.

Uses

LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs.

LCL-161Supplier

DKMbiochem.Co. Ltd Gold
Tel
15901859516
Email
sales@DKMbiochem.com
Nanjing Machido Pharmaceutical Technology Co., Ltd. Gold
Tel
19556085883
Email
sales@machidopharma.com
Changzhou Bojia Biomedical Technology Co., Ltd. Gold
Tel
2122619822
Email
czbjpharma@126.com
Shanghai Boyle Chemical Co., Ltd.
Tel
Email
sales@boylechem.com
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18934348241
Email
sales4.gd@hwrkchemical.com
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LCL-161(1005342-46-0)Related Product Information