ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Apoptosis > IAP inhibitors > LCL-161
LCL-161
LCL-161 Basic information
- Product Name:
- LCL-161
- Synonyms:
-
- LCL-161
- N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-MethylalaninaMide
- (2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide
- (S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)
- N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-(2S)-propanamide
- (2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide LCL 161
- LCL161, 98%, inhibitor of Apoptosis Protein (IAP) family of proteins
- CS-987
- CAS:
- 1005342-46-0
- MF:
- C26H33FN4O3S
- MW:
- 500.63
- Product Categories:
-
- Inhibitors
- Mol File:
- 1005342-46-0.mol
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LCL-161 Chemical Properties
- Boiling point:
- 713.7±60.0 °C(Predicted)
- Density
- 1.245±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
- form
- solid
- pka
- 14.25±0.46(Predicted)
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LCL-161 Usage And Synthesis
Description
LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins.
Uses
LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs.
LCL-161Supplier
DKMbiochem.Co. Ltd Gold
- Tel
- 15901859516
- sales@DKMbiochem.com
Nanjing Machido Pharmaceutical Technology Co., Ltd. Gold
- Tel
- 19556085883
- sales@machidopharma.com
Changzhou Bojia Biomedical Technology Co., Ltd. Gold
- Tel
- 2122619822
- czbjpharma@126.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
BeiJing Hwrk Chemicals Limted
- Tel
- 0757-86329057 18934348241
- sales4.gd@hwrkchemical.com