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5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

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5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Basic information

Product Name:
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
Synonyms:
  • N4-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxycytidine
  • N-[1-[5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-hydroxy-oxolan-2-yl]-2-oxo-pyrimidin-4-yl]benzamide
  • 5'-O-DIMETHOXYTRITYL-N-BENZOYL-DESOXYCYTI-DINE, 98+%
  • 5'-O-(4,4'-Dimethoxytrityl)-N-benzoyl-2'-deoxycytidine
  • N-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-ribofuranosyl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
  • N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxycytidine
  • N-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxycytidine
  • N4-Bz-DMT-dC
CAS:
67219-55-0
MF:
C37H35N3O7
MW:
633.69
EINECS:
266-605-9
Product Categories:
  • Biochemicals and Reagents
  • Building Blocks
  • C12 to C30+
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Nucleoside Analogs
  • Biochemistry
  • Nucleosides and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • Nucleic acids
  • Nucleosides
  • Nucleotides
  • Oligonucleotides
  • Pyrimidines
  • Organics
  • PNS
Mol File:
67219-55-0.mol
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5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Chemical Properties

Melting point:
119 °C
Boiling point:
668.71°C (rough estimate)
Density 
1.2234 (rough estimate)
refractive index 
58 ° (C=1, MeOH)
storage temp. 
2-8°C
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
pka
8.67±0.20(Predicted)
form 
powder to crystaline
color 
White to Almost white
Water Solubility 
100μg/L at 20℃
BRN 
601627
LogP
5.3 at 20℃
CAS DataBase Reference
67219-55-0(CAS DataBase Reference)
EPA Substance Registry System
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- (67219-55-0)
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Safety Information

Hazard Codes 
Xn,Xi,T
Risk Statements 
40-36/37/38-20/21/22-46-45
Safety Statements 
36/37-36-26-22-45-53
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
1
F 
1-3-10
HS Code 
29349990

MSDS

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5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Usage And Synthesis

Chemical Properties

Off-white powder

Uses

5''-O-(4,4''-Dimethoxytrityl)-N4-benzoyl-2''-deoxycytidine (CAS# 67219-55-0) is a cytidine nucleoside derivative, and has been used as a reactant with synthetic modified DNA and RNA, such as in the site-selective RNA activation by acridine-modified oligodeoxynucleotides in metal-ion catalyzed hydrolysis.

Uses

N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine has been used as research tool for anti-viral and anti-cancer studies.

General Description

The 3′-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite derivatives of N4-benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine (DMT-dCBz) participates in Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides.

Flammability and Explosibility

Not classified

5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidineSupplier

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5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine(67219-55-0)Related Product Information