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D-AMPHETAMINE HYDROCHLORIDE

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D-AMPHETAMINE HYDROCHLORIDE Basic information

Product Name:
D-AMPHETAMINE HYDROCHLORIDE
Synonyms:
  • DEXTRO-AMPHETAMINE
  • D-AMPHETAMINE
  • D-AMPHETAMINE HYDROCHLORIDE
  • C07884
  • S(+)-Amphetamine, 1.0 mg/mL
  • (aS)-a-Methyl-benzeneethanamine
  • d-a-Methylphenethylamine
  • DELTA-AMPHETAMINE
CAS:
51-64-9
MF:
C9H13N
MW:
135.21
EINECS:
200-112-1
Product Categories:
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
51-64-9.mol
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D-AMPHETAMINE HYDROCHLORIDE Chemical Properties

Melting point:
25°C
Boiling point:
208.93°C (estimate)
Density 
0.9354 (estimate)
refractive index 
1.5087 (estimate)
Flash point:
9℃
storage temp. 
-20°C
pka
pKa 9.90 (Uncertain)
color 
Oil
EPA Substance Registry System
Dextroamphetamine (51-64-9)
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
16-36/37-45
RIDADR 
3249
WGK Germany 
1
HazardClass 
6.1(a)
PackingGroup 
II
Hazardous Substances Data
51-64-9(Hazardous Substances Data)
Toxicity
LD50 orl-rat: 38 mg/kg TXAPA9 18,185,71
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D-AMPHETAMINE HYDROCHLORIDE Usage And Synthesis

Uses

CNS stimulant; anorexic. More active isomer of Amphetamine. Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake. Controlled substance (stimulant)

Definition

ChEBI: A 1-phenylpropan-2-amine that has S configuration.

brand name

Dexampex (Teva); Dexedrine (GlaxoSmithKline); Dextrostat (Shire); Ferndex (Ferndale);Adiparthrol;Afatin;Amfe-dyn;Amphaetex;Bipheramine;Curban;D-amfetasul;Dexadrine;Dexamed;Dexedrina;Dexten;Dextro-profetamine;Drinamyl;Durophet-m;Maxiton;Mephadexamine-r;Mephadexamin-r;Obetrol;Obotan;Proptan;Robese;Simpamina d;Steladex;Stil-2;Synatan.

World Health Organization (WHO)

Schedule II of the 1971 Convention on Psychotropic Substances. See WHO comment for amfetamine. (Reference: (UNCPS2) United Nations Convention on Psychotropic Substances (II), , , 1971)

Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Chronic exposure causes central nervous system damage and blood-pressure effects. When heated to decomposition it emits toxic NOx. See other amphetamine entries.

Synthesis

The compound can be prepared by optical resolution of amphetamineor directly from (-)-norephedrine by conversion to the (+)-chloroamine followed by catalytic hydrogenation .

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