(R)-N-Boc-3-hydroxyadaMantylglycine
(R)-N-Boc-3-hydroxyadaMantylglycine Basic information
- Product Name:
- (R)-N-Boc-3-hydroxyadaMantylglycine
- Synonyms:
-
- Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-hydroxy-, (αR)-
- (alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxytricyclo[3.3.1.1(3,7)]decane-1-acetic acid
- (R)-N-Boc-3-hydroxyadaMantylglycine
- Boc-3-hydroxy-1-adamantyl-L-glycine
- (R)-N-Boc-2-(3-hydroxyadamant-1-yl)glycine
- Boc-3-hydroxy-1-adamantyl-glycine
- "(a-R)-a--[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-Tricyclo[3.3.1.13,7]decane-1-acetic acid"
- Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-
- CAS:
- 1334321-39-9
- MF:
- C17H27NO5
- MW:
- 325.4
- Mol File:
- 1334321-39-9.mol
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(R)-N-Boc-3-hydroxyadaMantylglycine Chemical Properties
- Melting point:
- >280°C (dec.)
- Boiling point:
- 497.3±20.0 °C(Predicted)
- Density
- 1.296±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 3.93±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
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(R)-N-Boc-3-hydroxyadaMantylglycine Usage And Synthesis
Uses
Boc-3-hydroxy-1-adamantyl-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
Uses
Boc-3-hydroxy-1-adamantyl-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
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ChemStrong Scientific Co.,Ltd
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- 0755-0755-66853366 13670046396
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(R)-N-Boc-3-hydroxyadaMantylglycine(1334321-39-9)Related Product Information
- 3-Hydroxy-1-AdaMantane Carboxylic Acid
- Saxagliptin Impurity 34
- Hydroxy Saxagliptin
- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3R,5R)-
- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3S,5R)-
- (S) - N- Boc- adamantylglycine
- Saxagliptin Impurity 16
- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)-
- 1H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione, hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)-
- (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXAMIDE 2,2,2-TRIFLUOROACETIC ACID
- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)-
- (1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetate
- 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)-
- (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID
- 3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one, 6-aMino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)-
- Saxagliptin
- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3R,5R)-
- Saxagliptin Impurity 15