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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-

BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-

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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Basic information

Product Name:
BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-
Synonyms:
  • BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-
  • Bosentan USP Related Compound B
  • p-tert-butyl-N-[6-(hydroxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzene sulfonamide
  • Bosentan USP RC B
  • Bosentan IMpurity D
  • Bosentan Related CoMpound B
  • N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide
  • Bosentan Related Compound B (15 mg) (4-(tert-butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide)
CAS:
174227-14-6
MF:
C25H25N5O5S
MW:
507.56
Mol File:
174227-14-6.mol
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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Chemical Properties

Melting point:
>218°C (dec.)
Boiling point:
690.0±65.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
4.48±0.50(Predicted)
color 
Pale Beige to Light Beige
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Safety Information

HS Code 
2935909550
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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Usage And Synthesis

Uses

O-Deshydroxyethyl Bosentan (Bosentan USP Related Compound B) is an impurity of Bosentan (B675900); a mixed endothelin receptor antagonist. Used as a vasodilator and antihypertensive.

BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-Supplier

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