Carboxyatractyloside
Carboxyatractyloside Basic information
- Product Name:
- Carboxyatractyloside
- Synonyms:
-
- (2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
- Carboxyatractyloside tripotassium salt
- Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-
- Carboxyatractylosidetripotassiumsal
- Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-
- CAS:
- 77228-71-8
- MF:
- C31H46O18S2
- MW:
- 770.81
- Product Categories:
-
- reagent
- standard substance
- chemical reagent
- herbal extract
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- Mol File:
- 77228-71-8.mol
More
Less
Carboxyatractyloside Chemical Properties
- Density
- 1.58±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: ≥10mg/mL
- pka
- -3?+-.0.18(Predicted)
- form
- solid
- color
- white
More
Less
More
Less
Carboxyatractyloside Usage And Synthesis
Uses
Carboxyatractyloside potassium salt has been used as an activator of Ca2+-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.
Biochem/physiol Actions
Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.
target
Calcium Channel | P450 (e.g. CYP17)
CarboxyatractylosideSupplier
ShangHai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847 13636370518
- shyysw007@163.com
Chengdu Biopurify Phytochemicals Ltd.
- Tel
- +86-028-82633397 18982077548
- cwb1@biopurify.cn
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
TargetMol Chemicals Inc.
- Tel
- 021-021-33632979 15002134094
- marketing@targetmol.com
Cheng Du Pufeide Biotechnology Co., Ltd.
- Tel
- 028-82610909 13388174823
- scglp@glp-china.com
More
Less
Carboxyatractyloside(77228-71-8)Related Product Information
- 3-Dimethylamino-1-propanol
- Acetoin
- Cupric acetate monohydrate
- Madecassoside
- ATRACTYLOSIDE POTASSIUM SALT
- ALLEOSIDE A
- Terrestrosin D
- xanthatin
- Xanthiside
- roburic acid
- Poricoic acid A(F)
- Pachymic acid
- 1,3,5-Tricaffeoylquinic acid
- Terrestrosin K
- Madecassic acid
- dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate