cis-Atovaquone Chemical Properties

Melting point:

>40°C (dec.)

Boiling point:

535.0±50.0 °C(Predicted)

Density 

1.349±0.06 g/cm3(Predicted)

storage temp. 

Room Temperature, under inert atmosphere

solubility 

Chloroform (Slightly), Dichloromethane (Slightly, Acetonitrile)

pka

5.01±0.10(Predicted)

form 

Solid

color 

Pale Yellow to Light Yellow

Safety Information

WGK Germany 

3

cis-Atovaquone Usage And Synthesis

Uses

cis-Atovaquone is the cis-isomer of Atovaquone (A793500), a hydroxynaphthoquinone derivative that inhibits mitochondrial electron transport.

Definition

ChEBI: Atovaquone is a naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position. It has a role as an antimalarial, an antifungal agent, an EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor, an EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor and an EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor. It is a member of monochlorobenzenes and a hydroxy-1,4-naphthoquinone.

cis-Atovaquone(137732-39-9)Related Product Information

• Atovaquone
• O-Methyl Atovaquone
• Atovaquone Impurity 6
• trans-4-(4-Chlorophenyl)-1-acetylcyclohexane
• Atovaquone Impurity 4
• 5,6-trans Travoprost
• 15-Keto Travoprost
• 5-TRANS FLUPROSTENOL
• 15(S)-Fluprostenol isopropyl ester
• 4'-ACETYLCYCLOHEXYL CHLOROBENZENE
• cis-4-(4-Chlorophenyl)cyclohexanecarboxylic Acid
• 2-(4'-chloro-2,3,4,5-tetrahydro-[1,1'-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione
• 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
• Atovaquone Impurity 5
• Deschloro Atovaquone
• Atovaquone EP Impurity A
• cis-Atovaquone-d4 (Atovaquone EP Impurity B-d4)
• Didehydroatovaquone isomer