Basic information Safety Supplier Related

Methotrexate γ-Methyl Ester

Basic information Safety Supplier Related

Methotrexate γ-Methyl Ester Basic information

Product Name:
Methotrexate γ-Methyl Ester
Synonyms:
  • Methotrexate EP Impurity H
  • Methotrexate Impurity 8(EP-H)
  • Methotrexate EP Impurity H (Methotrexate-5-Monomethyl Ester)
  • Methotrexate-5-monomethyl ester
  • Methotrexate EP Impurity H(Amethopterin EP Impurity H)
  • Methotrexate γ-Methyl Ester (Impurity H)
  • (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
  • Methotrexate Impurity H
CAS:
67022-39-3
MF:
C21H24N8O5
MW:
468.47
Product Categories:
  • Aromatics, Chiral Reagents, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
67022-39-3.mol
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Methotrexate γ-Methyl Ester Chemical Properties

Melting point:
170-174 °C
Density 
1.459±0.06 g/cm3(Predicted)
solubility 
Aqueous Base (Slightly, Sonicated), DMSO (Slightly, Heated)
pka
3.43±0.10(Predicted)
form 
Solid
color 
Light Yellow to Orange
Stability:
Hygroscopic
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Methotrexate γ-Methyl Ester Usage And Synthesis

Uses

Methotrexate γ-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

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