2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester
2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester Basic information
- Product Name:
- 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester
- Synonyms:
-
- 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester
- (Z)-Methyl 3-(Methoxy(phenyl)Methylene)-2-oxoindoline-6-carboxylate
- 3-(Methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
- (E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester
- Methyl 3-[Methoxy(Phenyl)Methylene]-2-Oxoindoline-6-Carboxylate (Under Development)
- CAS:
- 1160293-22-0
- MF:
- C18H15NO4
- MW:
- 309.32
- Product Categories:
-
- Intermediate of BIBF-1120 and PKI587
- Mol File:
- 1160293-22-0.mol
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2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester Chemical Properties
- Melting point:
- >220oC (dec.)
- Boiling point:
- 523.8±50.0 °C(Predicted)
- Density
- 1.273±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 10.62±0.20(Predicted)
- form
- Solid
- color
- Light Yellow
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2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester Usage And Synthesis
Uses
(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity.
2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl esterSupplier
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