Ubrogepant
Ubrogepant Basic information
- Product Name:
- Ubrogepant
- Synonyms:
-
- Ubrogepant
- MK-1602
- MK-1602 Ubrogepant
- Spiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide, 1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxo-, (3'S)-
- Ubrogepant API
- Ubrogepant D5
- (S)-N-((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
- MK1602,MK 1602,Ubrogepant,inhibit,Inhibitor,Calcitonin gene-related peptide receptor,CGRP Receptor
- CAS:
- 1374248-77-7
- MF:
- C29H26F3N5O3
- MW:
- 549.54
- Product Categories:
-
- API
- 1374248-77-7
- Mol File:
- 1374248-77-7.mol
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Ubrogepant Chemical Properties
- Boiling point:
- 729.4±60.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 11.08±0.20(Predicted)
- color
- White to off-white
- InChIKey
- DDOOFTLHJSMHLN-ZQHRPCGSSA-N
- SMILES
- C12C[C@@]3(C(=O)NC4=NC=CC=C43)CC1=CC(C(N[C@H]1C[C@@H](C3=CC=CC=C3)[C@@H](C)N(CC(F)(F)F)C1=O)=O)=CN=2
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Ubrogepant Usage And Synthesis
Uses
Ubrogepant, is a new drug possible used for the treatment of migraine.
Synthesis
Synthesis route of Ubrogepant
in vivo
Ubrogepant (0.06-100 μg/kg; intravenous injection; 1-3 times) inhibits Capsaicin (HY-10448)-induced dermal vasodilation in a concentration- and time-dependent manner in rhesus monkeys with an EC50 of 3.19 nM[1].
UbrogepantSupplier
Jiangsu Vcare PharmaTech Co., Ltd. Gold
- Tel
- 025-58741518 13327700685
- sales@vcarepharmatech.com
Kaifeng Mingren Pharmaceutical Co.,LTD Gold
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- 0371-65741762
- sales@hasunny.com
ChengDu TongChuangYuan Pharmaceutical Co.Ltd Gold
- Tel
- 028-83379370 13880556291
- tcy@tcypharm.com
J & K SCIENTIFIC LTD.
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- 18210857532; 18210857532
- jkinfo@jkchemical.com
Anhui Lianchuang Biological Medicine Co.,Ltd
- Tel
- 0551-68779238 18056025720
- sales3@lcywhx.com