Basic information Safety Supplier Related

2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-

Basic information Safety Supplier Related

2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- Basic information

Product Name:
2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-
Synonyms:
  • 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-
  • (3R,5S)-5-biphenyl-4-ylMethyl-3-Methylpyrrolidin-2-one
  • valsartan + sacubitril impurity
  • Sacubitril Impurity 37
  • LCZ696(valsartan + sacubitril) impurity 7
  • Cyclic impurity of Sacubitril
  • LCZ696-7
  • (3R,5S)-
CAS:
1038924-70-7
MF:
C18H19NO
MW:
265.35
Mol File:
1038924-70-7.mol
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2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- Chemical Properties

Melting point:
148 - 150°C
Boiling point:
474.0±24.0 °C(Predicted)
Density 
1.083±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
16.35±0.60(Predicted)
form 
Solid
color 
White to Off-White
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2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- Usage And Synthesis

Uses

Sacubitril Impurity 1 is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.

2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-Supplier

Adamas Reagent, Ltd.
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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UHN Shanghai Research & Development Co., Ltd.
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