2,3-Dihydrobenzofuran Chemical Properties

Melting point:

-21°C

Boiling point:

188-189 °C (lit.)

Density 

1.065 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.549(lit.)

Flash point:

152 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

alcohol: soluble

form 

clear liquid

color 

Colorless to Yellow to Green

Specific Gravity

1.065

Merck 

14,2559

BRN 

111928

InChIKey

HBEDSQVIWPRPAY-UHFFFAOYSA-N

LogP

2.140

CAS DataBase Reference

496-16-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzofuran, 2,3-dihydro-(496-16-2)

EPA Substance Registry System

Coumaran (496-16-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25-26

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29329995

MSDS

• Language:English Provider:Coumaran
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,3-Dihydrobenzofuran Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

2,3-dihydrobenzofuran is widely used in the synthesis of tricyclic compounds and is also an intermediate raw material for the synthesis of some important drugs. It is used in the synthesis of antitumor agents benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, etc.

Definition

ChEBI: 2,3-dihydrobenzofuran is a member of the class of 1-benzofurans that is the 2,3-dihydroderivative of benzofuran. It has a role as a metabolite.

General Description

Biotransformation of 2,3-dihydrobenzofuran using intact cells of Pseudomonas putida UV4 has been investigated. 2,3-Dihydrobenzofuran is the intermediate formed during catalytic hydrodeoxygenation of benzofuran.

2,3-Dihydrobenzofuran(496-16-2)Related Product Information

• 2H-Indeno[5,4-b]furan-8-ethanamine, 1,6,7,8-tetrahydro-, (8R)-
• Ethyl 3-(2,3-Dihydrobenzofuran-5-yl)propenoate
• WBYZCPYZHMZPHD-UHFFFAOYSA-N
• 4-bromo-1,2,6,7-tetrahydro-8H-Indeno[5,4-b]furan-8-one
• 3-(2,3-DIHYDRO-BENZOFURAN-5-YL)-PROPIONIC ACID ETHYL ESTER
• 2,3-Dihydrobenzo[b]furan-5-carbaldehyde
• Benzofuran
• Potassium hydrogen phthalate
• Tetrahydrofuran
• STERIGMATOCYSTIN
• 2,3-Dihydrobenzofuran-3-one
• THEBAINE
• AFLATOXIN G1
• Ethofumesate
• NALORPHINE HYDROCHLORIDE
• MARITIMEIN
• 2-COUMARANONE
• (-)-USNIC ACID