PIPERITONE
PIPERITONE Basic information
- Product Name:
- PIPERITONE
- Synonyms:
-
- 1-P-MENTHEN-3-ONE
- 4-ISOPROPYL-1-METHYL-1-CYCLOHEXEN-3-ONE
- 6-isopropyl-3-methylcyclohex-2-enone
- P-MENTH-1-EN-3-ONE 92%
- piperitone,3-methyl-6-(1-methylethyl)-2-cyclohexen-1-one,p-menth-1-en-3-one
- PIPERITONE(SG)
- ALPHA-PIPERITONE
- PARA-MENTH-1-EN-3-ONE
- CAS:
- 89-81-6
- MF:
- C10H16O
- MW:
- 152.23
- EINECS:
- 201-942-7
- Product Categories:
-
- Biochemistry
- Monocyclic Monoterpenes
- Terpenes
- Mol File:
- 89-81-6.mol
PIPERITONE Chemical Properties
- Melting point:
- -29 °C
- Boiling point:
- 233°C
- Density
- 0,93 g/cm3
- FEMA
- 2910 | D-PIPERITONE
- refractive index
- -60 ° (C=4, benzene)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Oil
- color
- Colourless to Pale Yellow
- Odor
- at 10.00 % in dipropylene glycol. herbal minty camphor medicinal
- Odor Type
- herbal
- JECFA Number
- 435
- Merck
- 7473
- LogP
- 2.4
- EPA Substance Registry System
- Piperitone (89-81-6)
Safety Information
- Safety Statements
- 23-24/25
- RTECS
- OT0257000
- HS Code
- 2914.29.5000
PIPERITONE Usage And Synthesis
Chemical Properties
Monocyclic monoterpenes. There is a pair of enantiomers, both of which are naturally occurring. The right enantiomer has a camphoraceous odor, oily liquid, boiling point 232-235°C, relative density 0.9344, refractive index 1.4848, spin [α]20D +49.13°. Left spin body boiling point 109.5-110.5 ℃ (1.99kPa), relative density 0.9324, refractive index 1.4832, often in two optical isomers are present in a variety of essential oils.
Uses
Piperitone is a monoterpene compound that has a fresh minty camphor-like odour, and naturally occurs in extracts of commercial oil of peppermint. Piperitone is also used as a starting material in the synthesis of Thymol (T413000), a phenolic compound that is used for its antibacterial properties. The cyclic ketone is more commonly used in flavour compositions, particularly in spice complexes with Caraway, Estragon, etc., and in fruit complexes with mint flavours, etc. Now and then, it has become “fashionable” in dentifrice preparations where larger amounts are used. The concentration normally used is equivalent to about 1 to 20 ppm in the finished product.
Production Methods
Piperitone is produced:
by isolation from Japanese Mint oil (dextro-Piperitone),
by isolation from Eucalyptus dives oil (laevo-Piperitone),
by hydrogenation of Diosphenol,
by reduction of 5-Methyl-2-iso-propylanisole with Sodium in liquid Ammonia.
laevo-Piperitone can also be produced from laevo-beta-Pinene via l-Limonene, by hydrogenation to /-Carvomenthene, and via 4 further intermediate steps to Piperitone.
Definition
ChEBI: A p-menthane monoterpenoid that is cyclohex-2-en-1-one substituted by a methyl group at position 3 and an isopropyl group at position 6.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
in vivo
The insecticidal activity of crude essential oil extracted from Cymbopogon schoenanthus and of its main constituent, Piperitone, is assessed on different developmental stages of Callosobruchus maculatus (C. maculatus). Piperitone is toxic to C. maculatus adults with a LC50 value of 1.6 μL/L. Piperitone inhibits the development of newly laid eggs and of neonate larvae, but is less toxic than the crude extract to individuals developing inside the seeds. Piperitone shows the strongest ovicidal activity. All the eggs were aborted at 6.7 μL/L. Piperitone (10 μM) kills all the neonate larvae[1].
| Animal Model: | Fifty pairs of C. maculatus adults[1] |
| Dosage: | 6.7, 10, 16.7 or 33.3 μL/L |
| Administration: | 24 hours |
| Result: | Piperiton was more toxic than crude oil because the LC50 recorded was 1.6 μL/L for Piperitone vs. 2.7 μL/L for the crude oil. |
PIPERITONE Preparation Products And Raw materials
Preparation Products
Raw materials
PIPERITONESupplier
- Tel
- 400-0066400 13621662912
- 422131432@qq.com
- Tel
- 15755158983
- yunhefei@foxmail.com
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
- Tel
- 4006356688 18621169109
- market03@meryer.com
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
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