(5R,6S,7S,13aS,16R,17R)-5,6,7,8-Tetrahydro-17-hydroxy-1,2,3-trimethoxy-6,7,16,17-tetramethyl-5,13-(epoxybutanoxy)benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-18-one Usage And Synthesis

Uses

Gomisin E, a dibenzocyclooctadiene lignan isolated from the fruits of Schizandra chinensis, inhibits NFAT transcription with an IC50 of 4.73 μM[1][2].

References

[1] YUKINOBU IKEYA, et al. The Constituents of Schizandra chinensis BAILL. V. The Structures of Four New Lignans, Gomisin N, Gomisin O, Epigomisin O and Gomisin E, and Transformation of Gomisin N to Deangeloylgomisin B.
[2] Im Seon Lee, et al. Lignans with Inhibitory Activity against NFAT Transcription from Schisandra chinensis.

(5R,6S,7S,13aS,16R,17R)-5,6,7,8-Tetrahydro-17-hydroxy-1,2,3-trimethoxy-6,7,16,17-tetramethyl-5,13-(epoxybutanoxy)benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-18-one(72960-21-5)Related Product Information

• Gomisin S
• (-)Gomisin L1
• Angeloyl-(+)-gomisin K3
• Angeloyl O iso gomisin
• Isogomisin O
• Angeloylgomisin H
• gomisin J
• Gomisin B
• gomisin D
• Benzoylgomisin H
• Angeloylgomisin O
• Gomisin T
• Tigloylgomisin H
• Gomisin L2
• (6S,7S,12aR)-5,6,7,8-Tetrahydro-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene-1,7-diol
• GOMISING
• Methylisogomisin O
• TrigloylgoMisin P