Basic information Safety Supplier Related

PEG9-t-butly ester

Basic information Safety Supplier Related

PEG9-t-butly ester Basic information

Product Name:
PEG9-t-butly ester
Synonyms:
  • HO-PEG8-CH2CH2COOTBU
  • t-Butyl 3-Hydroxy(peg8)propionate
  • HO-PEG8-COOtBu
  • tert-Butyl 1-Hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
  • PEG9-t-butly ester
  • 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
  • OH-PEG8-CH2CH2COOtBu
  • OH-PEG8-TBA
CAS:
1334177-84-2
MF:
C23H46O11
MW:
498.6
Product Categories:
  • peg
Mol File:
1334177-84-2.mol
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PEG9-t-butly ester Chemical Properties

Boiling point:
549.5±45.0 °C(Predicted)
Density 
1.083±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Water, DMSO, DMF, DCM
pka
14.36±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C23H46O11/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h24H,4-21H2,1-3H3
InChIKey
RBRDLMWBCQQRIQ-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCO
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PEG9-t-butly ester Usage And Synthesis

Description

Hydroxy-PEG8-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Hydroxy-PEG8-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC 50

PEGs

PEG9-t-butly esterSupplier

Adamas Reagent, Ltd.
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400-6009262 16621234537
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Chengdu Pukang Biotechnology Co., Ltd
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+86-028-82550498 +86-19102685862
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T&W GROUP
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021-61551611 13296011611
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Nanjing Junnahe Biopharmaceutical Co., Ltd
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025-58367986 17351780683
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amy.xiang@ally-chem.com
Hunan HuaTeng Pharmaceutical Co., Ltd.,
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400-8592883
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