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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid

(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid

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(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid Basic information

Product Name:
(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid
Synonyms:
  • Rivaroxaban Impurity 80
  • Rivaroxaban-10
  • Rivaroxaban Impurity 19/Rivaroxaban Amine Impurity/(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid
  • Rivaroxaban impurity K: diamine
  • (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid
  • 2-[2-[[(5-Chloro-2-thienyl)carbonyl][4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]acetic Acid
  • Rivaroxaban EP Impurity I
  • Acetic acid, 2-[2-[[(5-chloro-2-thienyl)carbonyl][4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-
CAS:
1151893-81-0
MF:
C24H21Cl2N3O7S2
MW:
598.48
Mol File:
1151893-81-0.mol
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(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid Chemical Properties

Boiling point:
843.9±65.0 °C(Predicted)
Density 
1.542±0.06 g/cm3(Predicted)
solubility 
Chloroform, DMSO (Slightly), Methanol (Slightly)
pka
3.37±0.10(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid Usage And Synthesis

Uses

Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde is an intermediate in synthesizing Rivaroxaban Pseudodimer (R538015), which is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.

(S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acidSupplier

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