METHYL TRANS-4-HYDROXYMETHYLCYCLOHEXANECARBOXYLATE Chemical Properties

Boiling point:

250.7±13.0 °C(Predicted)

Density 

1.058±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)

pka

15.05±0.10(Predicted)

form 

Oil

color 

Colourless

METHYL TRANS-4-HYDROXYMETHYLCYCLOHEXANECARBOXYLATE Usage And Synthesis

Uses

Methyl 4-(Hydroxymethyl)cyclohexanecarboxylate is a useful reagent in the synthesis and biopharmaceutical evaluation of imatinib analogs.

References

[1] Patent: US2012/165347, 2012, A1. Location in patent: Page/Page column 43
[2] Patent: CN105566324, 2016, A. Location in patent: Paragraph 0379; 0380; 0381; 0382
[3] Patent: WO2014/28597, 2014, A2. Location in patent: Page/Page column 54
[4] Patent: US2015/191434, 2015, A1. Location in patent: Paragraph 0295
[5] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 6, p. 1564 - 1568

METHYL TRANS-4-HYDROXYMETHYLCYCLOHEXANECARBOXYLATE(13380-85-3)Related Product Information

• dimethyl bicyclo[2.2.2]octane-1,4-dicarboxylate
• BICYCLO[2.2.2]OCTANE-1,4-DICARBOXYLIC ACID HEMIMETHYL ESTER
• DIETHYL 2,5-DIOXOBICYCLO[2.2.2]OCTANE-1,4-DICARBOXYLATE
• DIMETHYL 1,4-CUBANEDICARBOXYLATE
• Dimethyl 1,4-cyclohexanedicarboxylate
• Columbin
• DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE
• ISOCOLUMBIN
• TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER
• CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE
• Diallyl 1,4-Cyclohexanedicarboxylate (cis- and trans- mixture)
• TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID DIETHYL ESTER
• 4-METHOXYCARBONYLCUBANECARBOXYLIC ACID
• 1-(2-CHLOROETHYL)CYCLOHEXANE-1,4-DICARBOXYLIC ACID DIMETHYL ESTER
• METHYL 4-HYDROXYMETHYLCUBANECARBOXYLATE
• phyllanthoside
• METHYL TRANS-4-HYDROXYMETHYLCYCLOHEXANECARBOXYLATE
• PHYTOLACCOSIDEB