P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Chemical Properties

storage temp. 

-20°C

solubility 

H2O: soluble50mg/mL

form 

powder

color 

white to off-white

Safety Information

WGK Germany 

3

HS Code 

29349990

P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Usage And Synthesis

Chemical Properties

White powder

Uses

P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt has been used as a adenylate kinase inhibitor and as a component of pre-AMPPNP rigor solution for treating muscle fibres.

Biochem/physiol Actions

A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.

P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT(75522-97-3)Related Product Information

• Adenosine 5'-monophosphate monohydrate
• Lithium dihydrogen phosphate
• adenosine 5'-tetraphosphate
• 2'-Deoxyadenosine 5'-phosphate
• dilithium dihydrogen diphosphate
• P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
• 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
• Adenosine triphosphate
• ADP
• 2'-Deoxyadenosine 5'-triphosphate
• P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
• 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE LITHIUM SALT