ChemicalBook > Product Catalog > API > Antineoplastic agents > Other antineoplastic Drugs > 2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Basic information
- Product Name:
- 2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
- Synonyms:
-
- 2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
- (±)-1,2-Bis(3,5-diox-opiperazinyl)propane
- Razoxane
- ICRF
- ICRF-159
- Eucardion
- ICI-59118
- ICRF-187
- CAS:
- 21416-87-5
- MF:
- C11H16N4O4
- MW:
- 268.27
- Mol File:
- 21416-87-5.mol
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2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Chemical Properties
- Melting point:
- 233.5°C
- Boiling point:
- 411.43°C (rough estimate)
- Density
- 1.2576 (rough estimate)
- refractive index
- 1.6081 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly)
- form
- Solid
- color
- White
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2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Usage And Synthesis
Uses
Razoxane is an inhibitor of Topo II.
Definition
ChEBI: Razoxane is a N-alkylpiperazine.
Safety Profile
Suspected carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. Human systemic effects by ingestion: nausea, thrombocytopenia, leukopenia. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Preparation Products And Raw materials
Raw materials
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2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-(21416-87-5)Related Product Information
- Dexrazoxane
- Pemetrexed Disodium
- (S)-(-)-1,2-Diaminopropane dihydrochloride
- Dexrazoxane hydrochloride
- 4-(2-AMINO-ETHYL)-PIPERAZIN-2-ONE
- 1,1'-ethylenedipiperazine
- 4,4-(2,3-BUTANEDIYL)-BIS(2,6-PIPERAZINEDIONE)
- ETHYLIMINUM
- 4-methylpiperazine-2,6-dione
- 1-(2-DIETHYLAMINOETHYL)PIPERAZINE
- 2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
- Piperazine-2,6-dione