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ChemicalBook >  Product Catalog >  API >  Antineoplastic agents >  Other antineoplastic Drugs >  2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-

2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-

Basic information Safety Supplier Related

2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Basic information

Product Name:
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
Synonyms:
  • 2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
  • (±)-1,2-Bis(3,5-diox-opiperazinyl)propane
  • Razoxane
  • ICRF
  • ICRF-159
  • Eucardion
  • ICI-59118
  • ICRF-187
CAS:
21416-87-5
MF:
C11H16N4O4
MW:
268.27
Mol File:
21416-87-5.mol
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2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Chemical Properties

Melting point:
233.5°C
Boiling point:
411.43°C (rough estimate)
Density 
1.2576 (rough estimate)
refractive index 
1.6081 (estimate)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly)
form 
Solid
color 
White
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2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Usage And Synthesis

Uses

Razoxane is an inhibitor of Topo II.

Definition

ChEBI: Razoxane is a N-alkylpiperazine.

Safety Profile

Suspected carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. Human systemic effects by ingestion: nausea, thrombocytopenia, leukopenia. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Preparation Products And Raw materials

Raw materials

2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-Supplier

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