Pyridazin-3-ylmethanol Chemical Properties

Melting point:

66 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))

Boiling point:

150 °C(Press: 1 Torr)

Density 

1.227±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

form 

solid

pka

13.41±0.10(Predicted)

color 

Yellow

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

22

Hazard Note 

Irritant

HS Code 

2933998090

Pyridazin-3-ylmethanol Usage And Synthesis

Synthesis

To a solution of ethyl pyridazine-3-carboxylate (0.641 g, 4.21 mmol) in THF (20 mL) at 0 °C has added a solution of lithium aluminium hydride in tetrahydrofuran (1.0 M, 4.21 mL, 4.21 mmol) dropwise. The resulting suspension was stirred for 30 min. Solid Na2S04 *10 H20 was added, and the mixture was diluted with EtOAc and stirred for lh. The mixture was filtered through a pad of celite, and the residual solid was washed with EtOAc several times. The filtrate was concentrated under reduced pressure. The crude product was purified by silica gel chromatography to afford the product Pyridazin-3-ylmethanol as a brown solid (120 mg 26 percent).

Pyridazin-3-ylmethanol(37444-46-5)Related Product Information

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• Cyclohexanemethanol
• Thioridazine
• Sulfachloropyridazine sodium
• 4-Pyridazinecarboxylic acid
• 3-PYRIDAZINECARBALDEHYDE,97%
• 4-Cyanopyridazine
• 4-PYRIDAZINECARBOXAMIDE
• ETHYL 4-PYRIDAZINECARBOXYLATE
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• PYRIDAZINE-4-CARBALDEHYDE
• Pyridazine-4-carboxylic acid methyl ester
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• Pyridazine
• 3-Pyridazinecarboxylic acid
• 6-Chloropyridazine-3-carboxylic acid
• 4-OXO-1H-CINNOLINE-3-CARBOXYLIC ACID