sir2-like 5 Chemical Properties

storage temp. 

-70°C

form 

buffered aqueous glycerol solution

biological source

human

Specific Activity

17.0-26.5RLU/min·ng

Safety Information

Hazard Codes 

T

Risk Statements 

61

Safety Statements 

53-45

sir2-like 5 Usage And Synthesis

Uses

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Biological Activity

Sirtuins are NAD+-dependent deacetylases. Sirtuin 5 (SIRT5) catalyzes the degradation of negatively charged acylated substrates. It also possesses desuccinylase, demalonylase and deglutarylase activities. The protein is overexpressed in non-small cell lung cancer (NSCLC) and may have a role in cancer growth.

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