Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Organic Chemistry >  Carboxylic acids and derivatives >  15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid

Basic information Safety Supplier Related

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid Basic information

Product Name:
15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid
Synonyms:
  • BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
  • Boc-NH-PEG4-CH2CH2COOH
  • 15-(Boc-aMino)-4,7,10,13-tetraoxapentadecanoic acid
  • 3-[2-[2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
  • 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(1,1-dimethylethyl) ester
  • N-(tert-Butyloxycarbonyl)-15-amino-4,7,10,13-tetraoxapentanedecanoic acid
  • 2,2-DiMethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid
  • t-Boc-N-amido-PEG4-acid
CAS:
756525-91-4
MF:
C16H31NO8
MW:
365.42
Product Categories:
  • ADCs Linkers
  • PEG
Mol File:
756525-91-4.mol
More
Less

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid Chemical Properties

Boiling point:
504.5±50.0 °C(Predicted)
Density 
1.124±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
pka
4.28±0.10(Predicted)
form 
Oil
color 
Colorless to light yellow
λmax
254nm(lit.)
InChI
InChI=1S/C16H31NO8/c1-16(2,3)25-15(20)17-5-7-22-9-11-24-13-12-23-10-8-21-6-4-14(18)19/h4-13H2,1-3H3,(H,17,20)(H,18,19)
InChIKey
YCEYBRZRNOJORY-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCC(O)=O
More
Less

Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29225090
More
Less

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid Usage And Synthesis

Description

t-Boc-N-amido-PEG4-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

Yellow oil

Uses

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid is used as a substitution variant of cocaine esterase with improved stability and its use in treatment of cocaine overdose.

Reactivity Profile

reagent type: cross-linking reagent, reaction type: Pegylations

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acidSupplier

Shanghai Huici Pharmaceutical Technology Co., LTD Gold
Tel
19372841038 19372841038
Email
lixing@pharmahuici.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Email
sales@pharmablock.com
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Email
Sales-CN@TCIchemicals.com
Energy Chemical
Tel
021-021-58432009 400-005-6266
Email
sales8178@energy-chemical.com