ChemicalBook > Product Catalog > Organic Chemistry > Carboxylic acids and derivatives > 15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid
15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid
15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid Basic information
- Product Name:
- 15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid
- Synonyms:
-
- BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
- Boc-NH-PEG4-CH2CH2COOH
- 15-(Boc-aMino)-4,7,10,13-tetraoxapentadecanoic acid
- 3-[2-[2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(1,1-dimethylethyl) ester
- N-(tert-Butyloxycarbonyl)-15-amino-4,7,10,13-tetraoxapentanedecanoic acid
- 2,2-DiMethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid
- t-Boc-N-amido-PEG4-acid
- CAS:
- 756525-91-4
- MF:
- C16H31NO8
- MW:
- 365.42
- Product Categories:
-
- ADCs Linkers
- PEG
- Mol File:
- 756525-91-4.mol
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15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid Chemical Properties
- Boiling point:
- 504.5±50.0 °C(Predicted)
- Density
- 1.124±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- 2-8°C
- pka
- 4.28±0.10(Predicted)
- form
- Oil
- λmax
- 254nm(lit.)
- InChI
- InChI=1S/C16H31NO8/c1-16(2,3)25-15(20)17-5-7-22-9-11-24-13-12-23-10-8-21-6-4-14(18)19/h4-13H2,1-3H3,(H,17,20)(H,18,19)
- InChIKey
- YCEYBRZRNOJORY-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCC(O)=O
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Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29225090
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15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid Usage And Synthesis
Description
t-Boc-N-amido-PEG4-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Chemical Properties
Yellow oil
Uses
15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid is used as a substitution variant of cocaine esterase with improved stability and its use in treatment of cocaine overdose.
Reactivity Profile
reagent type: cross-linking reagent, reaction type: Pegylations
15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acidSupplier
Hangzhou HanLai Biochemical Technology Co., Ltd. Gold
- Tel
- 0571-86101219 13675881727
- sales@leobiochem.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
PharmaBlock Sciences (Nanjing),Inc.
- Tel
- 400-0255188 4000255188
- sales@pharmablock.com
TCI (Shanghai) Development Co., Ltd.
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
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