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Mepivacaine hydrochloride

Basic information Safety Supplier Related

Mepivacaine hydrochloride Basic information

Product Name:
Mepivacaine hydrochloride
Synonyms:
  • Mepivacaine Hydrochloride (200 mg)
  • Ropivacaine base Mepivacaine HCL
  • (1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride
  • 1-methyl-2’,6’-pipecoloxylididehydrochloride
  • Mepivacaine HCl USP
  • 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride
  • 2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI, 8CI)
  • 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (9CI)
CAS:
1722-62-9
MF:
C15H22N2O.ClH
MW:
282.81
EINECS:
217-023-9
Product Categories:
  • API
  • Sodium channel
  • Amines
  • Aromatics
  • Heterocycles
  • Analgesic series
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
1722-62-9.mol
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Mepivacaine hydrochloride Chemical Properties

Melting point:
255-257°C (dec.)
storage temp. 
Refrigerator
solubility 
H2O: soluble20mg/mL, clear
form 
powder
color 
white to beige
CAS DataBase Reference
1722-62-9(CAS DataBase Reference)
EPA Substance Registry System
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (1722-62-9)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
RIDADR 
UN 2811 6.1 / PGIII
RTECS 
TK6475000
HS Code 
29333990
Toxicity
LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg)
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Mepivacaine hydrochloride Usage And Synthesis

Chemical Properties

White Solid

Uses

anesthetic (local)

Uses

An anti-inflammatory and analgesic

Definition

ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic.

brand name

Arestocaine Hydrochloride (Solvay Pharmaceuticals); Carbocaine (Hospira); Isocaine Hydrochloride(Novocol); Polocaine (AstraZeneca); Polocaine (Dentsply); Scandonest (Deproco).

Biological Functions

Mepivacaine hydrochloride (Carbocaine) is longer acting than lidocaine and has a more rapid onset of action (3–5 minutes). Topical application is not effective. It has been widely used in obstetrics, but its use has declined recently because of the early transient neurobehavioral effects it produces. Adverse reactions associated with mepivacaine are generally similar to those produced by other local anesthetics. It can be used with epinephrine or levonordefrin (dental use only).

Safety Profile

skin irritant. Questionable carcinogen with

Mepivacaine hydrochlorideSupplier

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