Basic information Safety Supplier Related

N-Desmethyl Regorafenib

Basic information Safety Supplier Related

N-Desmethyl Regorafenib Basic information

Product Name:
N-Desmethyl Regorafenib
Synonyms:
  • N-Desmethyl Regorafenib
  • Regorafenib impurity O
  • Regorafenib N-Desmethyl Impurity
  • Regorafenib M-4 metabolite
  • 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-
  • Regorafenib metabolite M4
  • Regorafenib Impurity 53
  • 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide
CAS:
1343498-72-5
MF:
C20H13ClF4N4O3
MW:
468.79
Mol File:
1343498-72-5.mol
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N-Desmethyl Regorafenib Chemical Properties

Melting point:
>195°C (dec.)
Boiling point:
496.8±45.0 °C(Predicted)
Density 
1.552±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
12.06±0.70(Predicted)
form 
Solid
color 
Pale Orange to Pale Red
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N-Desmethyl Regorafenib Usage And Synthesis

Uses

N-Desmethyl Regorafenib is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.

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