Sitagliptin EP Impurity B Chemical Properties

InChIKey

UOKMPNRCGWVMBY-XAAIUDFWNA-N

SMILES

P(O)(O)(O)=O.C(N1CCN2C(C(F)(F)F)=NN=C2C1)(=O)C[C@H](N)CC1=CC(F)=CC=C1F |&1:21,r|

Sitagliptin EP Impurity B Usage And Synthesis

Uses

4-Desfluoro Sitagliptin is a metabolite of Sitagliptin phosphate (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Uses

Sitagliptin EP Impurity B is an impurity of the synthetic drug Sitagliptin. It can be used as an impurity reference to detect the quality of drugs, and is often used in pharmaceutical synthesis. Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 diabetes. Sitagliptin is not for treating type 1 diabetes

Sitagliptin EP Impurity B(1345822-87-8)Related Product Information

• 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine
• rac-Sitagliptin EP Impurity B HCl
• rac-Sitagliptin
• n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
• Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)-
• 2-(3-(methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol
• Sitagliptin Impurity 34
• 2,4,5-Trifluorobenzaldehyde
• 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)-
• Sitagliptin
• Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
• (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione
• Sitagliptin N-Sulfate
• BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID
• Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate
• Sitagliptin N-Boc IMpurity
• Sitagliptin Impurity 35
• (S)-Sitagliptin Phosphate