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Trimebutine

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Trimebutine Basic information

Product Name:
Trimebutine
Synonyms:
  • API Trimebutine
  • 3,4,5-TRIMETHOXYBENZOATE,-2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL
  • 3,4,5-TRIMETHOXYBENZOIC ACID 2-[DIMETHYLAMINO]-2-PHENYLBUTYL ESTER
  • TRIMEBUTIN
  • TRIMEBUTINE
  • trimebutine free base
  • Trimebutine hydrochloride
  • TRIMEBUTINE3.4.5-TRIMETHOXYBENZOATE,-2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL
CAS:
39133-31-8
MF:
C22H29NO5
MW:
387.47
EINECS:
254-309-2
Product Categories:
  • API
  • ACTIVE PHARMACEUTICAL INGREDIENTS
Mol File:
39133-31-8.mol
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Trimebutine Chemical Properties

Melting point:
78-80°C
Boiling point:
513.42°C (rough estimate)
Density 
1.1998 (rough estimate)
refractive index 
1.5614 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
pka
7.29±0.50(Predicted)
color 
White to Off-White
Water Solubility 
10g/L
Merck 
14,9699
CAS DataBase Reference
39133-31-8(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HS Code 
2922.19.0900

MSDS

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Trimebutine Usage And Synthesis

Uses

Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.

Uses

Trimebutine is an opioid receptor agonist and an antispasmodic agent (1,2). It is used to treat acute and chronic abdominal pain.

Definition

ChEBI: 3,4,5-trimethoxybenzoic acid [2-(dimethylamino)-2-phenylbutyl] ester is a trihydroxybenzoic acid.

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