4-Chlorobenzyl bromide Chemical Properties

Melting point:

48-52 °C (lit.)

Boiling point:

107-108°C 8mm

Density 

1.570±0.06 g/cm3(Predicted)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

Chloroform, Dichloromethane (Slightly)

form 

Crystalline Low Melting Solid

color 

White

Water Solubility 

Insoluble in water.

Sensitive 

Lachrymatory

BRN 

606497

InChIKey

KQNBRMUBPRGXSL-UHFFFAOYSA-N

CAS DataBase Reference

622-95-7(CAS DataBase Reference)

NIST Chemistry Reference

4-Chlorobenzyl bromide(622-95-7)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 1759 8/PG 2

WGK Germany 

3

Hazard Note 

Corrosive/Lachrymatory

HazardClass 

6.1

PackingGroup 

II

HS Code 

29049090

MSDS

• Language:English Provider:1-(Bromomethyl)-4-chlorobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Chlorobenzyl bromide Usage And Synthesis

Chemical Properties

White crystalline low melting solid

Uses

4-Chlorobenzyl bromide is used as pharmaceutical intermediate.

Uses

4-Chlorobenzyl bromide may be used to synthesize 1-(4-chlorobenzyl)-2-(pyrrolidin-1-yl-methyl)-1H-benzimidazole dihydrochloride

General Description

4-Chlorobenzyl bromide undergoes carbonylation in the presence of dimer of chloro(1,5-cyclooctadiene)rhodium(I) to yield the corresponding phenylacetic acid. It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.

4-Chlorobenzyl bromide(622-95-7)Related Product Information

• 4-Chlorobenzyl chloride
• 4-Chlorobenzyl cyanide
• 1,2-Dichloro-4-(chloromethyl)benzene
• BRETYLIUM TOSYLATE
• 3-Chlorobenzyl chloride
• Benzyl bromide
• Ethidium bromide
• 4-Methoxybenzylchloride
• Benzyl chloroformate
• Allyl bromide
• 4-Fluorobenzyl chloride
• 2-Chlorobenzyl chloride
• BCDMH
• Chlorobenzene
• Rocuronium bromide
• 4-Nitrobenzyl chloroformate
• Chlorobromoisocyanurate
• Sodium bromate