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2-Hydroxy-6-methylpyridine

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2-Hydroxy-6-methylpyridine Basic information

Product Name:
2-Hydroxy-6-methylpyridine
Synonyms:
  • 6-Methyl-2(1H)-pyridone
  • 6-Methyl-2-hydroxypyridine
  • 6-Methyl-2-pyridyl alcohol
  • 6-Methylpyridinone
  • 6-METHYL-2-PYRIDINONE
  • 6-METHYLPYRIDIN-2(1H)-ONE
  • AKOS BBS-00002969
  • TIMTEC-BB SBB004345
CAS:
3279-76-3
MF:
C6H7NO
MW:
109.13
EINECS:
221-919-5
Product Categories:
  • Pyridines
  • Pyridine
  • Pyridines, Pyrimidines, Purines and Pteredines
  • bc0001
Mol File:
3279-76-3.mol
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2-Hydroxy-6-methylpyridine Chemical Properties

Melting point:
157-159 °C (lit.)
Boiling point:
131-133C
Density 
1.1143 (rough estimate)
refractive index 
1.5040 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
Crystalline Powder
pka
12.12±0.10(Predicted)
color 
White to cream
BRN 
107073
InChI
InChI=1S/C6H7NO/c1-5-3-2-4-6(8)7-5/h2-4H,1H3,(H,7,8)
InChIKey
JEAVIRYCMBDJIU-UHFFFAOYSA-N
SMILES
C1(=O)NC(C)=CC=C1
CAS DataBase Reference
3279-76-3(CAS DataBase Reference)
NIST Chemistry Reference
2(1H)-Pyridinone, 6-methyl-(3279-76-3)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-36-22
WGK Germany 
3
10
HazardClass 
IRRITANT
HS Code 
29333999

MSDS

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2-Hydroxy-6-methylpyridine Usage And Synthesis

Chemical Properties

white to cream-colored crystalline powder

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 1186, 1949 DOI: 10.1021/ja01172a014

General Description

2-Hydroxy-6-methylpyridine reacts with carboxylic acids RCOOH to give an equilibrium mixture of products M(2)(O(2)CR)(n)(mhp)(4-n) where R = 2-thienyl and phenyl. mhp is the anion formed from deprotonation of 2-hydroxy-6-methylpyridine.

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