Basic information Safety Supplier Related

Biotin-PEG4-PFP ester

Basic information Safety Supplier Related

Biotin-PEG4-PFP ester Basic information

Product Name:
Biotin-PEG4-PFP ester
Synonyms:
  • Biotin-PEG4-PFP ester
  • 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, 2,3,4,5,6-pentafluorophenyl ester
  • 2,3,4,5,6-pentafluorophenyl 1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-3,6,9,12-tetraoxapentadecan-15-oate
CAS:
1334172-58-5
MF:
C27H36F5N3O8S
MW:
657.65
Mol File:
1334172-58-5.mol
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Biotin-PEG4-PFP ester Chemical Properties

Boiling point:
804.9±65.0 °C(Predicted)
Density 
1.321±0.06 g/cm3(Predicted)
form 
Solid
pka
13.90±0.40(Predicted)
color 
White to off-white
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Safety Information

HS Code 
3404200000
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Biotin-PEG4-PFP ester Usage And Synthesis

Uses

Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

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