Ivabradine Impurity 1 Hydrochloride Chemical Properties

Melting point:

72-75 °C(Solv: toluene (108-88-3))

Boiling point:

479.0±45.0 °C(Predicted)

Density 

1.087±0.06 g/cm3(Predicted)

solubility 

soluble in Dichloromethane, Methanol

pka

10.33±0.10(Predicted)

Ivabradine Impurity 1 Hydrochloride Usage And Synthesis

Uses

1,3,4,5-Tetrahydro-7,8-dimethoxy-3-[3-(methylamino)propyl]-2H-3-benzazepin-2-one is an intermediate of Ivabradine Hydrochloride (I940500), which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.

Ivabradine Impurity 1 Hydrochloride(85175-77-5)Related Product Information

• Nalfurafine
• N-Desmethyl Ivabradine D6 HCl
• N-DeMethyl Ivabradine Hydrochloride
• 8-DeMethyl Ivabradine
• Ivabradine hydrochloride
• 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one
• Hydroxy Ivabradine
• Ivabradine Impurity 21 HCl
• Ivabradine Impurity 5
• ent-Ivabradine Hydrochloride
• C-(3,4-DIMETHOXY-BICYCLO[4.2.0]OCTA-1(6),2,4-TRIEN-7-YL)-METHYLAMINE
• (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
• 1-Bromo-3-chloropropane
• Ivabradine-d3 Hydrochloride
• 7-DeMethyl Ivabradine
• 4,5-Dimethoxy-1-cyanobenzocyclobutane
• Ivabradine IMpurity
• (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one