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Methylprednisolone acetate

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Methylprednisolone acetate Basic information

Product Name:
Methylprednisolone acetate
Synonyms:
  • depo-medrone
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-
  • METHYLPREDNISOLONEACETATE,MICRONIZED,USP
  • 21-Acetoxy-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
  • 6a-Methylprednisolone 21-acetate
  • DepMedalone 40
  • DepMedalone 80
  • Mepred
CAS:
53-36-1
MF:
C24H32O6
MW:
416.51
EINECS:
200-171-3
Product Categories:
  • API
  • Miscellaneous Biochemicals
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • Steroid and Hormone
  • 53-36-1
Mol File:
53-36-1.mol
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Methylprednisolone acetate Chemical Properties

Melting point:
192-195°C
alpha 
D20 +101° (dioxane)
Boiling point:
454.82°C (rough estimate)
Density 
1.1156 (rough estimate)
refractive index 
1.4593 (estimate)
storage temp. 
Refrigerator
solubility 
Practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent).
pka
12.41±0.70(Predicted)
form 
Solid
color 
White to Off-White
CAS DataBase Reference
53-36-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
63-62
Safety Statements 
36/37-24/25
HS Code 
32041200
Toxicity
LD50 oral in rat: > 10gm/kg
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Methylprednisolone acetate Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

6α-Methyl Prednisolone 21-Acetate is used as a glucocorticoid.

Uses

Methylprednisolone acetate is used as a glucocorticoid.

Definition

ChEBI: An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

brand name

Medrol (Pharmacia & Upjohn).

Methylprednisolone acetateSupplier

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