Basic information Safety Supplier Related

N-Methylcyclohexylamine

Basic information Safety Supplier Related

N-Methylcyclohexylamine Basic information

Product Name:
N-Methylcyclohexylamine
Synonyms:
  • 1-Methylcyclohexylamine
  • Cyclohexanamine,N-methyl-
  • Cyclohexylamine, N-methyl-
  • Cyclohexylmethylamine
  • cyclohexyl-methyl-amine
  • Methylcyclohexylamine
  • methylcyclohexylamine,[corrosivelabel]
  • N-METHYLCYCLOHEXYLAMINE
CAS:
100-60-7
MF:
C7H15N
MW:
113.2
EINECS:
202-869-3
Product Categories:
  • fine chemicals
  • pharmaceutical
Mol File:
100-60-7.mol
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N-Methylcyclohexylamine Chemical Properties

Melting point:
-9--7 °C (lit.)
Boiling point:
149 °C (lit.)
Density 
0.868 g/mL at 25 °C (lit.)
vapor density 
4 (vs air)
vapor pressure 
11 mm Hg ( 40 °C)
refractive index 
n20/D 1.456(lit.)
Flash point:
85 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
54g/l
form 
Liquid
pka
11.03±0.20(Predicted)
Specific Gravity
0.855 (20/4℃)
color 
Clear colorless to yellow
PH
12 (10g/l, H2O, 20℃)
explosive limit
2.2-10.5%(V)
Water Solubility 
5.4 g/100 mL (20 ºC)
Sensitive 
Air Sensitive
BRN 
1523664
Dielectric constant
3.6400000000000001
CAS DataBase Reference
100-60-7(CAS DataBase Reference)
NIST Chemistry Reference
Cyclohexanamine, N-methyl-(100-60-7)
EPA Substance Registry System
Cyclohexanamine, N-methyl- (100-60-7)
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Safety Information

Hazard Codes 
C
Risk Statements 
10-21/22-35-20/21/22
Safety Statements 
16-26-36/37/39-45
RIDADR 
UN 2734 8/PG 2
WGK Germany 
1
RTECS 
GX1529000
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29213099

MSDS

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N-Methylcyclohexylamine Usage And Synthesis

Chemical Properties

clear colourless to yellow liquid

Uses

Intermediate, solvent, acid acceptor.

Uses

N-Methylcyclohexanamine is a chemical reagent used in the synthesis of Mps1 kinase inhibitors used in cancer research. Also used in the synthesis of antituberculosis agents as indole-2-carboxamides.

Uses

N-Methylcyclohexylamine is used as a component of vulcanization accelerators, but the market size is relatively small.

Preparation

N-Methylcyclohexylamine can be prepared by a procedure similar to that used for cyclohexylamine, i.e., by hydrogenation of methylaniline over a supported nickel catalyst or from cyclohexanone and methylamine under hydrogenation conditions. Cyclohexylamine reacts with methanol over copper, zinc, or copper – calcium catalysts.

Definition

ChEBI: A secondary aliphatic amine having methyl and cyclohexyl as the two alkyl groups.

General Description

A water-white liquid. Slightly soluble in water and floats on water. A strong irritant to skin and eyes. Corrosive. Used as a solvent.

Air & Water Reactions

Flammable. Slightly soluble in water.

Reactivity Profile

METHYL CYCLOHEXYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Hazard

Toxic. Strong irritant to tissue.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

N-Methylcyclohexylamine Preparation Products And Raw materials

Raw materials

Preparation Products

N-MethylcyclohexylamineSupplier

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