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4-Oxo-4H-1-benzopyran-2-carboxylic acid

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4-Oxo-4H-1-benzopyran-2-carboxylic acid Basic information

Product Name:
4-Oxo-4H-1-benzopyran-2-carboxylic acid
Synonyms:
  • 4-oxo-4h-1-benzopyran-2-carboxylicaci
  • 4-OXO-4H-1-BENZOPYRAN-2-CARBOXYLIC ACID
  • 4-OXO-4H-BENZOPYRAN-2-CARBOXYLIC ACID
  • 4-OXO-4H-CHROMENE-2-CARBOXYLIC ACID
  • CHROMONE-2-CARBOXYLIC ACID
  • CHROMOCARB
  • LABOTEST-BB LT00454887
  • 4-Oxo-4H-1-benzopyran-2-carboxylic acid, 97% 5GR
CAS:
4940-39-0
MF:
C10H6O4
MW:
190.15
EINECS:
225-583-0
Product Categories:
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • FLUDARENE
Mol File:
4940-39-0.mol
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4-Oxo-4H-1-benzopyran-2-carboxylic acid Chemical Properties

Melting point:
260 °C (dec.)(lit.)
Boiling point:
285.64°C (rough estimate)
Density 
1.3366 (rough estimate)
refractive index 
1.5280 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
alcohol: soluble
form 
Powder
pka
2.28±0.20(Predicted)
color 
White to beige
Water Solubility 
sparingly soluble
Merck 
14,2237
BRN 
146442
CAS DataBase Reference
4940-39-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
DJ2476000
Hazard Note 
Irritant
HS Code 
29329990
Toxicity
LD50 intraperitoneal in mouse: 585mg/kg

MSDS

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4-Oxo-4H-1-benzopyran-2-carboxylic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

vascular protectant

Uses

Chromone-2-carboxylic acid is used in the cyclic form 3?-oxopyrazolidino[4?,5??2, 3]-chroman-4-one, gives the azide of chromone-2-carboxylic acid, the curtius rearrangement of which is used to synthesize a number of 2-acylaminochromones and it is an orally active antiallergic agent.

Uses

4-oxo-4H-1-Benzopyran-2-carboxylic Acid acts as an inhibitor of monoamine oxidase A & B. Also functions as a novel type of tyrosine phosphatase 1B inhibitor in studies, due to a structure derived from formylchromone.

Definition

ChEBI: 4-oxo-1-benzopyran-2-carboxylic acid is a member of chromones.

General Description

Nasal absorption of 4-oxo-4H-1-benzopyran-2-carboxylic acid has been investigated in the male Wistar rat.

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