Basic information Safety Supplier Related

1-(4-Nitrophenyl)piperazine

Basic information Safety Supplier Related

1-(4-Nitrophenyl)piperazine Basic information

Product Name:
1-(4-Nitrophenyl)piperazine
Synonyms:
  • Piperazine-Ph-NO2
  • 1-(4-nitrophenyl)piperazin-4-ium
  • AKOS BBS-00003599
  • 1-(P-NITROPHENYL)PIPERAZINE
  • 1-NITRO-4-(1-PIPERAZINYL)BENZENE
  • 1-(4-NITROPHENYL)PIPERAZINE
  • 1-(4-NITRO-PHENYL)-PIPERAZINE DIHYDROCHLORIDE
  • 1-(4-NITROPHENYL)PIPERAZINE HCL
CAS:
6269-89-2
MF:
C10H13N3O2
MW:
207.23
EINECS:
228-443-7
Product Categories:
  • CHIRAL CHEMICALS
  • Phenyls & Phenyl-Het
  • Nitrogen cyclic compounds
  • Building Blocks
  • Heterocyclic Building Blocks
  • Piperazines
  • Piperidines, Piperidones, Piperazines
  • pharmacetical
  • Phenyls & Phenyl-Het
  • Piperaizine
  • API intermediates
Mol File:
6269-89-2.mol
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1-(4-Nitrophenyl)piperazine Chemical Properties

Melting point:
131-133 °C (lit.)
Boiling point:
346.25°C (rough estimate)
Density 
1.1933 (rough estimate)
refractive index 
1.4830 (estimate)
pka
8.68±0.10(Predicted)
form 
Crystalline Powder, Crystals and/or Chunks
color 
White to beige to gray
InChIKey
VWOJSRICSKDKAW-UHFFFAOYSA-N
CAS DataBase Reference
6269-89-2(CAS DataBase Reference)
NIST Chemistry Reference
N-p-nitrophenylpiperazine(6269-89-2)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-37/39-24/25-36
RIDADR 
2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29335990

MSDS

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1-(4-Nitrophenyl)piperazine Usage And Synthesis

Chemical Properties

yellow to ochre powder

Uses

1-(4-Nitrophenyl)piperazine is a useful synthetic intermediate in the synthesis of Itraconazole (I937500); an orally active antimycotic structurally related to Ketoconazole. Also antifungal.

General Description

Inclusion interactions of 1-(4-nitrophenyl)piperazine with 4-sulfonatocalix[n]arenes were investigated by UV spectroscopy and fluorescence spectroscopy.

1-(4-Nitrophenyl)piperazine Preparation Products And Raw materials

Preparation Products

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