1-(3-Chlorphenyl)piperazine
1-(3-Chlorphenyl)piperazine Basic information
- Product Name:
- 1-(3-Chlorphenyl)piperazine
- Synonyms:
-
- RARECHEM AH CK 0071
- N-(3-CHLOROPHENYL)PIPERAZINE
- TIMTEC-BB SBB003579
- MCPP
- 1-(3-CHLORPHENYL)-PIPERAZINE
- 1-(3-CHLOROPHENYL)PIPERAZINE
- 1-(3-Chlorophenyl)piperazine 97%
- 1-(3-CHLOROPHENYL)PIPERAZINE (MCPP)
- CAS:
- 6640-24-0
- MF:
- C10H13ClN2
- MW:
- 196.68
- EINECS:
- 229-654-7
- Product Categories:
-
- FOR TRAZODONE'S PRODUCTION
- Various Metabolites and Impurities
- PHARMACEUTICAL INTERMEDIATES
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Piperazines
- Piperidines, Piperidones, Piperazines
- Piperaizine
- API intermediates
- Mol File:
- 6640-24-0.mol
More
Less
1-(3-Chlorphenyl)piperazine Chemical Properties
- Melting point:
- 210-214°C
- Boiling point:
- 105 °C
- Density
- 1.193
- refractive index
- 1,598-1,600
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Methanol (Sparingly)
- form
- Oil
- pka
- 8.85±0.10(Predicted)
- color
- Colourless to Orange
- LogP
- 2.468
- CAS DataBase Reference
- 6640-24-0(CAS DataBase Reference)
More
Less
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-36
- HazardClass
- IRRITANT
- HS Code
- 29339900
MSDS
- Language:English Provider:3-Chlorophenyl piperazine
More
Less
1-(3-Chlorphenyl)piperazine Usage And Synthesis
Chemical Properties
clear colorless to light yellow oily liquid
Uses
It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
Definition
ChEBI: A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Hazard
A poison.
More
Less
1-(3-Chlorphenyl)piperazine(6640-24-0)Related Product Information
- 1-(3-Chlorphenyl)piperazine
- 1-(M-CHLOROPHENYL) PIPERAZINE HYDROCHLORIDE,1-(3-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE
- N-(3,4-DICHLOROPHENYL)PIPERAZINE HYDROCHLORIDE
- 4-(4-Chlorophenyl)piperazine,1-(4-CHLOROPHENYL)PIPERAZINE
- 1-(2,3-DICHLOROPHENYL)PIPERAZINE HYDROBROMIDE
- 3-(4-CHLOROPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- 1-(2,5-Dichlorophenyl)piperazine dihydrochloride
- 1-(4-Chlorophenyl)piperazin-2-one
- 1-(2,4-DICHLOROBENZYL)PIPERAZINE
- 1-(3,5-DICHLOROPHENYL)PIPERAZINE
- 1-(4-CHLOROPHENYL)PIPERAZINE DIHYDROCHLORIDE,1-(4-CHLOROPHENYL)-PIPERAZINE 2HCL
- 1-(2,3-Dichlorophenyl)-piperazine
- 1-(3-CHLOROPROPYL)-4-(3-CHLOROPHENYL)PIPERAZINE HCL
- 1-(2-CHLOROPHENYL)PIPERAZINE,1-(o-Chlorophenyl)piperazine
- 1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE,1-(2-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE
- 1-(2,3-Dichlorophenyl)piperazine hydrochloride
- 1-(4-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE,1-(4-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE
- 1-(3-Chlorophenyl)piperazine hydrochloride