(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties

Melting point:

65-69 °C(lit.)

Boiling point:

364.1±17.0 °C(Predicted)

Density 

1.016±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

soluble in Chloroform

form 

powder to crystal

color 

White to Almost white

optical activity

[α]20/D 1.0°, c = 1 in chloroform

CAS DataBase Reference

125971-94-0(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29329990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

Atorvastatin Intermediate

Uses

(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate(125971-94-0)Related Product Information

• Dimethyl fumarate
• Dimethyl sulfoxide
• Isobutyl acetate
• tert-Butanol
• tert-Butyl chloroacetate
• tert-Butyl acetate
• Dimethylbenzylcarbinyl acetate
• tert-Butyl bromoacetate
• N,N-Dimethylformamide
• DL-sec-Butyl acetate
• Methyl 2,2-dimethylphenylacetate
• Butyl acetate
• tert-Butyl peroxyacetate
• ETHANE
• (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
• Atorvastatin calcium
• Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
• Atorvastatin