mPEG11-Br Chemical Properties

Boiling point:

564.5±45.0 °C(Predicted)

Density 

1.179±0.06 g/cm3(Predicted)

mPEG11-Br Usage And Synthesis

Biological Activity

m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

mPEG11-Br(1258596-39-2)Related Product Information

• MPEG11-SH
• 1,2-Dimethoxyethane
• mPEG12-Br
• 25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane
• m-PEG6-bromide
• mPEG16-Br
• m-PEG9-bromide
• 1-{2-[2-(2-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2-methoxy-ethane
• 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
• m-PEG11-acid
• 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontanoic acid
• H2N-PEG11-CH2CH2COOH
• m-PEG5-Ms
• FMoc-NH-PEG7-CH2CH2COOH
• azido-mPEG11
• m-PEG11-CHO
• m-PEG11-Mal
• m-PEG11-Ph-CHO