4-Benzyloxybromobenzene Chemical Properties

Melting point:

60-63 °C (lit.)

Boiling point:

166-167 °C/4 mmHg (lit.)

Density 

1.3883 (rough estimate)

refractive index 

1.5130 (estimate)

Flash point:

166-167°C/3mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol (Slightly, Heated)

form 

powder to crystal

color 

White to Orange to Green

BRN 

1371040

InChI

InChI=1S/C13H11BrO/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9H,10H2

InChIKey

OUQSGILAXUXMGI-UHFFFAOYSA-N

SMILES

C1(Br)=CC=C(OCC2=CC=CC=C2)C=C1

CAS DataBase Reference

6793-92-6(CAS DataBase Reference)

NIST Chemistry Reference

4-Benzyloxybromobenzene(6793-92-6)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-37

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29093090

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Benzyloxybromobenzene Usage And Synthesis

Chemical Properties

White Solid

Uses

1-Benzyloxy-4-Bromobenzene is used in preparation of arylalkenylpropargylamine derivatives as MAO-B inhibitors exhibiting neuroprotective action for treatment of neurodegenerative diseases.

Synthesis

The synthesis of 4-benzyloxybromobenzene was as follows: p-bromophenol, benzyl chloride, anhydrous potassium carbonate and potassium iodide were placed in a 250 ml three-necked flask and 170 ml of anhydrous ethanol was added. The reaction was heated and refluxed at 80?? for 6h with stirring, and was detected by TLC . TLC detection, the raw materials are basically reacted completely. The reaction was stopped and the reaction solution was poured into 1000ml distilled water. distilled water, stirred thoroughly to remove the residual inorganic salts. Filtering, the class white solid, anhydrous ethanol recrystallization, 50g off-white powder, yield 88.5%.

4-Benzyloxybromobenzene(6793-92-6)Related Product Information

• 4-Bromobenzotrifluoride
• 2-Bromobenzaldehyde
• 4-Methoxybenzylchloride
• 2-Bromobenzonitrile
• 4-Bromotoluene
• 1,4-Dibromobenzene
• 3-(4-Bromophenyl)propionic acid
• Bromoxynil octanoate
• 3-Bromofluorobenzene
• Bromobenzene
• 4-Methoxybenzyl alcohol
• HALFENPROX
• Benzyloxyacetyl chloride
• Bromoxynil
• 1,2-Dibromobenzene
• 4-Bromobenzaldehyde
• Bromine
• 1-Bromo-4-nitrobenzene