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Aprepitant Impurity 12

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Aprepitant Impurity 12 Basic information

Product Name:
Aprepitant Impurity 12
Synonyms:
  • Aprepitant impurity 21/Aprepitant N-Oxide
  • 5-([(2R,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)-4-oxido-morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
  • 3H-1,2,4-Triazol-3-one, 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl]-1,2-dihydro-, [2R-[2α(R*),3α]]- (9CI)
  • (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)morpholine 4-oxide
  • Aprepitant N-OxideQ: What is Aprepitant N-Oxide Q: What is the CAS Number of Aprepitant N-Oxide Q: What is the storage condition of Aprepitant N-Oxide Q: What are the applications of Aprepitant N-Oxide
  • (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)morpholine 4-oxide (Aprepitant impurity)
CAS:
172673-23-3
MF:
C23H21F7N4O4
MW:
550.43
Mol File:
172673-23-3.mol
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Aprepitant Impurity 12 Chemical Properties

solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
6.65±0.20(Predicted)
form 
Solid
color 
White to Off-White
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Aprepitant Impurity 12 Usage And Synthesis

Uses

Aprepitant N-Oxide is an impurity of Fosaprepitant (F727300), a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant (A729800) prodrug.

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