1-Bromopentane Chemical Properties

Melting point:

−95 °C(lit.)

Boiling point:

130 °C(lit.)

Density 

1.218 g/mL at 25 °C(lit.)

vapor density 

>1 (vs air)

refractive index 

n20/D 1.444(lit.)

Flash point:

88 °F

storage temp. 

Flammables area

solubility 

H2O: insoluble

form 

Liquid

color 

Clear colorless to light yellow

Water Solubility 

practically insoluble

Merck 

14,602

BRN 

1730981

Dielectric constant

6.3（10℃）

Stability:

Stable. Flammable. Incompatible with strong oxidizing agents, strong bases.

InChIKey

YZWKKMVJZFACSU-UHFFFAOYSA-N

CAS DataBase Reference

110-53-2(CAS DataBase Reference)

NIST Chemistry Reference

Pentane, 1-bromo-(110-53-2)

EPA Substance Registry System

Pentane, 1-bromo- (110-53-2)

Safety Information

Hazard Codes 

Xi,F,N,Xn

Risk Statements 

10-36/37/38-51/53-22

Safety Statements 

26-36-61-37/39-29-16

RIDADR 

UN 1993 3/PG 3

WGK Germany 

2

RTECS 

RZ9770000

Hazard Note 

Irritant/Flammable

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29033036

Toxicity

LD50 ipr-mus: 1250 mg/kg GTPZAB 20(12),52,76

MSDS

• Language:English Provider:Amyl bromide
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1-Bromopentane Usage And Synthesis

Chemical Properties

liquid

Uses

1-Bromopentane is used in a multitude of organic synthesis. It is used in iron-catalyzed alkylations of aromatic Grignard reagents via cross coupling.

Uses

1-Bromopentane is a chemical reagent used in a multitude of organic syntheses. It is used iron-catalyzed alkylations of aromatic Grignard reagents via cross coupling. It is used in the synthesis of α, γ-diketo acids as reversible inhibitors of Hepatitis C virus NS5b RNA polymerase.

Synthesis Reference(s)

Journal of the American Chemical Society, 86, p. 5037, 1964 DOI: 10.1021/ja01076a084

General Description

1-Bromopentane undergoes phase transfer catalysed alkylation reaction with 2′-hydroxy acetophenone using tetrabutyl ammonium bromide as catalyst.

Safety Profile

Moderately toxic byintraperitoneal route. Slightly toxic by inhalation. Whenheated to decomposition it emits toxic vapors of Br^-.

Purification Methods

Wash the bromide with conc H2SO4, then water, 10% Na2CO3 solution, again with water, dry with CaCl2 or K2CO3, and fractionally distil it just before use. [Beilstein 1 IV 312.]

1-Bromopentane(110-53-2)Related Product Information

• 1-Pentene
• 2-Methylbutane
• Pentane
• Cyclopentane
• 2-Bromo-2-methylpropane
• 1-Bromododecane
• iso-Bromopentane
• Isoamyl nitrite
• 1-Chloropentane
• Dimidium bromide
• Bromoacetaldehyde diethyl acetal
• Sodium pentanesulfonate
• Bromocyclopentane
• Ethidium bromide
• 1-Bromobutane
• Allyl bromide
• Rocuronium bromide
• 1-Bromohexadecane