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Linagliptin N-Acetyl Impurity

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Linagliptin N-Acetyl Impurity Basic information

Product Name:
Linagliptin N-Acetyl Impurity
Synonyms:
  • Linagliptin Impurity 34
  • Linagliptin N-Acetyl Impurity
  • N-[(3R)-1-[7-(2-Butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]acetamide
  • Linagliptin impurity 11/(R)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide
  • Acetamide, N-[(3R)-1-[7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]-
  • Linagliptin F
  • tert-butyl (R)-(1-(7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-6-oxo-6,7-dihydro-3H-purin-8-yl)piperidin-3-yl)carbamate
  • (R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide (Linagliptin Impurity)
CAS:
1803079-49-3
MF:
C27H30N8O3
MW:
514.58
Mol File:
1803079-49-3.mol
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Linagliptin N-Acetyl Impurity Chemical Properties

Density 
1.37±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form 
Solid
pka
15.70±0.20(Predicted)
color 
Light Yellow to Yellow
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Linagliptin N-Acetyl Impurity Usage And Synthesis

Uses

Linagliptin Acetamide is an impurity of linagliptin (L465900), which is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.

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