Biotin-PEG3-oxyamine CAS#: 1786206-22-1

Biotin-PEG3-oxyamine Basic information

Product Name:

Biotin-PEG3-oxyamine

Synonyms:

Biotin-PEG3-oxyamine
Biotin-PEG3-oxyamine HCl salt
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-

CAS:

1786206-22-1

MF:

C18H34N4O6S

MW:

434.55

Mol File:

1786206-22-1.mol

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Biotin-PEG3-oxyamine Chemical Properties

Boiling point:: 740.1±60.0 °C(Predicted)
Density: 1.189±0.06 g/cm3(Predicted)
pka: 13.90±0.40(Predicted)

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Biotin-PEG3-oxyamine Usage And Synthesis

Description

Biotin-PEG3-oxyamine is an aldehyde-reactive biotinylation reagent. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage.

Uses

Biotin-PEG3-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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