Acetylseneciphylline N-oxide Chemical Properties

pka

4.60±0.40(Predicted)

Acetylseneciphylline N-oxide Usage And Synthesis

Chemical Properties

Deriving from seneciphylline, acetylseneciphylline N-oxide has a role as a Jacobaea metabolite. Structurally, it is an acetate ester, a macrocyclic lactone, an olefinic compound, an organic heterotricyclic compound, a pyrrolizine alkaloid and a tertiary amine oxide. Acetylseneciphylline N-oxide is a pyrrolizine alkaloid that is seneciphylline in which the hydroxy hydrogen has been replaced by an acetyl group and the tertiary amino function has been oxidized to the corresponding N-oxide.

Uses

Acetylseneciphylline N-oxide is a pyrrolizine alkaloid that is seneciphylline in which the hydroxy hydrogen is replaced by an acetyl group and the tertiary amino function is oxidised to the corresponding N-oxide[1].

Definition

ChEBI: Acetylseneciphylline N-oxide is a pyrrolizine alkaloid that is seneciphylline in which the hydroxy hydrogen has been replaced by an acetyl group and the tertiary amino function has been oxidised to the corresponding N-oxide. It has a role as a Jacobaea metabolite. It is an acetate ester, a macrocyclic lactone, an olefinic compound, an organic heterotricyclic compound, a pyrrolizine alkaloid and a tertiary amine oxide. It is functionally related to a seneciphylline.

References

[1] Dandan Cheng, et al. The relationship between structurally different pyrrolizidine alkaloids and western flower thrips resistance in F(2) hybrids of Jacobaea vulgaris and Jacobaea aquatica. J Chem Ecol. 2011 Oct;37(10):1071-80. DOI:10.1007/s10886-011-0021-6
[2] Cheng D, et al. The relationship between structurally different pyrrolizidine alkaloids and western flower thrips resistance in F(2) hybrids of Jacobaea vulgaris and Jacobaea aquatica. J Chem Ecol. 2011 Oct;37(10):1071-80.

Acetylseneciphylline N-oxide(123844-00-8)Related Product Information

• senecionine N-oxide
• SENECIONINE
• Seneciphylline
• RETRORSINE
• Seneciphylline N-oxide