BDP FL maleimide
BDP FL maleimide Basic information
- Product Name:
- BDP FL maleimide
- Synonyms:
-
- BDP FL maleimide
- OEMKXDGSMCHMJQ-UHFFFAOYSA-N
- BDP FL maleimide/MAL
- Boron, [N-?[2-?(2,?5-?dihydro-?2,?5-?dioxo-?1H-?pyrrol-?1-?yl)?ethyl]?-?5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrole-?2-?propanamidato-?κN1]?difluoro-?, (T-?4)?-
- 3-(5,5-Difluoro-7,9-dimethyl-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)propanamide
- CAS:
- 773859-49-7
- MF:
- C20H21BF2N4O3
- MW:
- 414.21
- Mol File:
- 773859-49-7.mol
BDP FL maleimide Chemical Properties
- solubility
- Soluble in DMSO, DMF, DCM
- Appearance
- orange solid
- InChI
- InChI=1S/C20H21BF2N4O3/c1-13-11-14(2)26-17(13)12-16-4-3-15(27(16)21(26,22)23)5-6-18(28)24-9-10-25-19(29)7-8-20(25)30/h3-4,7-8,11-12H,5-6,9-10H2,1-2H3,(H,24,28)
- InChIKey
- OEMKXDGSMCHMJQ-UHFFFAOYSA-N
- SMILES
- C(C1=CC=C2C=C3C(=CC(=[N]3[B+3]([N-]21)([F-])[F-])C)C)CC(=O)NCCN1C(C=CC1=O)=O
BDP FL maleimide Usage And Synthesis
Description
BDP FL maleimide is a BDP FL linker containing a maleimide group, which selectively reacts with free thiol, sulfhydryl, or mercapto group via Michael addition to form a stable carbon sulfur bond.
BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, peptide modification, and can replace fluorescein for microscopy.
Uses
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy[1].
References
[1] Jakob W Buecheler, et al. Impact of Payload Hydrophobicity on the Stability of Antibody-Drug Conjugates. Mol Pharm. 2018 Jul 2;15(7):2656-2664. DOI:10.1021/acs.molpharmaceut.8b00177
Abs/Em Maxima
503/509 nm
Fluoresene quantum yield
0.97
Extinction Coefficient
92000
CF260
0.015
CF280
0.027
BDP FL maleimideSupplier
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- 021-68781987 13818305065
- sales@energybiopharma.com
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- 010-62651721 18610486005
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- 1-516-6625404
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- 021-61312847; 18021002903
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BDP FL maleimide(773859-49-7)Related Product Information
- BDP FL DBCO
- BDP FL tetrazine
- BDP R6G DBCO
- BDP R6G carboxylic acid
- BDP 650/665 X NHS ester
- BDP 558/568 alkyne
- BDP 650/665 alkyne
- BDP FL hydrazide
- BDP R6G amine
- BDP 558/568 carboxylic acid
- BDP 630/650 azide
- BDP TMR NHS ester
- BDP TR alkyne
- BDP 630/650 maleimide
- BDP FL alkyne
- BDP R6G maleimide
- BDP R6G alkyne