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(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane

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(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Basic information

Product Name:
(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane
Synonyms:
  • (2R, 3S)-1,2-EPOXY-3-N-(TERT-BUTOXYCARBONYL)AMINO-4-PHENYLBUTANE
  • (2r,3s)-3-(n-boc-amino)-1-oxirane-4-phenylbutane
  • (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane
  • [1(S)-BENZYL-2(R),3-EPOXYPROPYL]-CARBAMIC ACID TERT-BUTYL ESTER
  • THREO-N-BOC-L-PHENYLALANINE EPOXIDE
  • TERT-BUTYL (1S)-1-[(2R)-OXIRAN-2-YL]-2-PHENYLETHYLCARBAMATE
  • Tert-Butyl[(1S)-1-(2R)-Oxiranyl-2-Phenylethyl]carbamate
  • Carbamic acid,[(1S)-1-(2R)-oxiranyl-2-phenylethyl]-,1,1-dimethylethyl ester
CAS:
98760-08-8
MF:
C15H21NO3
MW:
263.34
EINECS:
619-374-7
Product Categories:
  • Heterocycles
  • chiral
  • Chiral Amino Epoxides
  • Aromatics Compounds
  • Aromatics
  • Chiral Reagents
Mol File:
98760-08-8.mol
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(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Chemical Properties

Melting point:
50-52°C
Boiling point:
398.8±25.0 °C(Predicted)
Density 
1.118±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.19±0.46(Predicted)
color 
White to Off-White
CAS DataBase Reference
98760-08-8(CAS DataBase Reference)
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Safety Information

HS Code 
29242998
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(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Usage And Synthesis

Chemical Properties

White Crystalline Powder

Uses

Atazanavir intermediate. Enantiomer R

Application

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane is an intermediate of the HIV-1 protease inhibitor atazanavir (sc-207305) and aslo an intermediate of amprenavir.

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