Basic information Safety Supplier Related

MVPQJUFFTWWKBT-LBDWYMBGSA-N

Basic information Safety Supplier Related

MVPQJUFFTWWKBT-LBDWYMBGSA-N Basic information

Product Name:
MVPQJUFFTWWKBT-LBDWYMBGSA-N
Synonyms:
  • MVPQJUFFTWWKBT-LBDWYMBGSA-N
  • L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]- (9CI)
  • Caspase 4,Inhibitor,Anti-inflammatory,ZYVADFMK,Caspase 1,Z YVAD FMK,Caspase,inhibit,anti-tumor
  • Z-YVAD-FMK, Irreversible caspase-1 inhibitor
  • Z-YVAD-FMK, 10 mM in DMSO
CAS:
210344-97-1
MF:
C31H39FN4O9
MW:
630.66
Mol File:
210344-97-1.mol
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MVPQJUFFTWWKBT-LBDWYMBGSA-N Chemical Properties

Boiling point:
945.2±65.0 °C(Predicted)
Density 
1.261±0.06 g/cm3(Predicted)
form 
Solid
pka
9.81±0.15(Predicted)
color 
White to off-white
Sequence
Z-Tyr-Val-Ala-Asp-FMK
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MVPQJUFFTWWKBT-LBDWYMBGSA-N Usage And Synthesis

Uses

Z-YVAD-FMK is a?cell-permeable?caspase-1 and -4 inhibitor with?anti-inflammatory and anti-tumor activities[1].

IC 50

Caspase

References

[1] Li H1,et al.Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.J Immunol. 2007 Apr 15;178(8):5271-6. DOI:10.4049/jimmunol.178.8.5271
[2] Avivi-Green C, et al. Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines.J Nutr. 2002 Jul;132(7):1812-8. DOI:10.1093/jn/132.7.1812

MVPQJUFFTWWKBT-LBDWYMBGSA-NSupplier

AdooQ Bioscience CHINA
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