(1S,2S)-(+)-1,2-Diaminocyclohexane Chemical Properties

Melting point:

40-43 °C (lit.)

alpha 

25.25 º (589nm, c=5, 1 M HCl)

Boiling point:

104-110 °C/40 mmHg (lit.)

Density 

0.951

refractive index 

1.4886

Flash point:

169 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

form 

Crystals or Powder

pka

10.76±0.70(Predicted)

color 

White to light beige

optical activity

[α]20/D +25°, c = 5 in 1 M HCl

Water Solubility 

soluble

Sensitive 

Air Sensitive

BRN 

2801645

InChIKey

SSJXIUAHEKJCMH-WDSKDSINSA-N

CAS DataBase Reference

21436-03-3(CAS DataBase Reference)

NIST Chemistry Reference

(1S,2S)-(+)-1,2-Diaminocyclohexane(21436-03-3)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3259 8/PG 3

WGK Germany 

3

F 

10-34

HazardClass 

8

PackingGroup 

III

HS Code 

29213000

MSDS

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• Language:English Provider:SigmaAldrich
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(1S,2S)-(+)-1,2-Diaminocyclohexane Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

suzuki reaction

Uses

For synthesis of optically active products

Uses

Versatile ligand for the formation of metal complexes. Used in the synthesis of chiral tropocoronands which have potential utility in asymmetric catalysis.

Purification Methods

Distil or recrystallise the diamine from pet ether under N2 or Ar. Store it as above. The 1S,2S-base D-tartrate salt has M 264.3, m 180 -1 8 4o(dec) and [] 25 -12.5o (c 4, H2O) from which the free base can be purified or optically enriched. It is a useful chiral synthon. [Fjii et al. J Chem Soc, Chem Commun 45 1985, Takahashi et al. Tetrahedron Lett 30 7095 1989, Hanassian et al. J Org Chem 58 1991 1993, Beilstein 13 III 7.]

(1S,2S)-(+)-1,2-Diaminocyclohexane(21436-03-3)Related Product Information

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