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3,4-Dibromopyridine

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3,4-Dibromopyridine Basic information

Product Name:
3,4-Dibromopyridine
Synonyms:
  • SPECS AC-907/25004343
  • 3,4-DIBROMOPYRIDINE
  • 3,4-Dibromopyridine98%
  • Pyridine, 3,4-dibromo-
  • 3,4-DIBROMOPYRIDINE ISO 9001:2015 REACH
  • 4-DIBROMOPYRIDINE
CAS:
13534-90-2
MF:
C5H3Br2N
MW:
236.89
EINECS:
800-799-3
Product Categories:
  • Pyridine
  • pharmacetical
  • Pyridines
  • Brominated heterocyclic series
Mol File:
13534-90-2.mol
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3,4-Dibromopyridine Chemical Properties

Melting point:
71-72 C
Boiling point:
239.9±20.0 °C(Predicted)
Density 
2.059±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
2.06±0.10(Predicted)
form 
powder to crystal
color 
White to Yellow to Orange
CAS DataBase Reference
13534-90-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
HazardClass 
IRRITANT
HS Code 
2933399990
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3,4-Dibromopyridine Usage And Synthesis

Uses

3,4-dibromopyridine is a vital organic compound that could synthesise virous azaindoles. 6-Azaindoles are formed through site-selective Pd-catalyzed Sonogashira reaction of 3,4-dibromopyridine with alkynes, followed by a Pd-catalyzed tandem C–N coupling and cyclization with amines. On the other hand, 5-azaindoles are obtained by a site-selective Pd-catalyzed C–N coupling reaction of 3,4-dibromopyridine with amines, followed by C–C coupling and cyclization with alkynes[1].

References

[1] N. Son. “Synthesis of 5- and 6-Azaindoles by Sequential Site-Selective Palladium-Catalyzed C–C and C–N Coupling Reactions.” Synlett 52 1 (2020): 1308–1312.

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