DL-Isoborneol Chemical Properties

Melting point:

212-214 °C (subl.)(lit.)

Boiling point:

214°C

Density 

0.8389 (rough estimate)

vapor pressure 

0.057-4.706Pa at 25℃

refractive index 

1.4710 (estimate)

FEMA 

2158 | ISOBORNEOL

Flash point:

200 °F

storage temp. 

2-8°C

solubility 

almost transparency in Methanol

pka

15.36±0.60(Predicted)

form 

Powder

color 

Yellow

Odor

at 10.00 % in dipropylene glycol. balsam camphor herbal woody

Odor Type

balsamic

Water Solubility 

insoluble

Merck 

14,5128

JECFA Number

1386

BRN 

4126091

LogP

2.32-2.92 at 20-25℃

CAS DataBase Reference

124-76-5(CAS DataBase Reference)

NIST Chemistry Reference

DL-Isoborneol(124-76-5)

EPA Substance Registry System

Isoborneol (124-76-5)

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

11-38

Safety Statements 

24/25

RIDADR 

UN 1312 4.1/PG 3

WGK Germany 

2

RTECS 

NP7300000

TSCA 

Yes

HazardClass 

4.1

HS Code 

29061900

Hazardous Substances Data

124-76-5(Hazardous Substances Data)

Toxicity

mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03209,

MSDS

• Language:English Provider:1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

DL-Isoborneol Usage And Synthesis

Description

Isoborneol has a piney, camphoraceous odor. May be prepared by the hydrolysis of isobomyl acetate, or by catalytic reduction of camphor (both d- and ι-isomers); the optically inactive compound can be prepared by treating camphene with a 1:1 mixture of sulfuric acid and glacial acetic acid and then hydrolyzing the isobomyl acetat.

Chemical Properties

Isoborneol has a piney, camphoraceous odor.

Chemical Properties

white to almost white crystalline powder

Occurrence

Reported found in the oil of Abies sibirica and a few other essences and in the essential oil from roots of Chamaeciparis formosensis. Also reported found in apple, papaya, blackberry, cinnamomum, ginger, thymus, cheeses, cognac, Ocimum basilicum, rosemary, temoe lawak (Curcuma xanthorriza Roxb.) turmeric, sage, clary sage, ashanti pepper, German chamomile oil, eucalyptus oil and mastic gum leaf oil

Uses

Used as a synthetic flavor, as a moth repellent, cold sore topical medication, muscle liniment, and steam-inhaled cough suppressant. It is also used in Used in perfumes.

Uses

Isoborneol is a monoterpene and a component of several plant essential oils, showed dual viricidal activity against herpes simplex virus 1 (HSV-1).

Definition

A geometrical isomer of borneol.

Preparation

By the hydrolysis of isobornyl acetate, or by catalytic reduction of camphor (both d- and l-isomers); the optically inactive compound can by prepared by treating camphene with a 1:1 mixture of sulfuric acid and glacial acetic acid and then hydrolyzing the isobornyl acetate

Aroma threshold values

Detection: 2.5 to 16 ppb

General Description

Isoborneol is a monoterpene and a known antioxidant, which is a component of several plant essential oils.

Flammability and Explosibility

Flammable

Purification Methods

Crystallise isoborneol from EtOH or pet ether (b 60-80o). It sublimes in a vacuum. The 4-nitrobenzoyl derivative has m 153o. [Yager & Morgan J Am Chem Soc 57 2081 1935, Beilstein 6 II 80, 6 III 299, 6 IV 281.]

DL-Isoborneol(124-76-5)Related Product Information

• Isomalt
• Isobornyl acetate
• Isodecanol
• Isophytol
• 2,2,6,6-Tetramethyl-4-piperidinol
• 6-O-ALPHA-D-GLUCOPYRANOSYL-D-GLUCITOL
• ISOMALTOSE
• Isosorbide
• 3-Methyl butynol
• 7-METHYL-1-OCTANOL
• Isoborneol methacrylate
• Isobornyl acrylate
• BORNEOL, CONTAINS 20% ISOBORNEOL: 70%,Borneol (contains ca. 20% Isoborneol)
• (+)-N,N-DICYCLOHEXYL-(1R)-ISOBORNEOL-10-SULFONAMIDE
• Isobornyl isovalerate
• (+)-(8,8-DICHLOROCAMPHORYLSULFONYL)OXAZIRIDINE
• Isoborneol, propionate
• L-BORNYL ACETATE