ChemicalBook > Product Catalog > Organic Chemistry > Amides > Acyclic polyamines and their derivatives > 2-(1H-Imidazol-1-yl)ethanamine
2-(1H-Imidazol-1-yl)ethanamine
2-(1H-Imidazol-1-yl)ethanamine Basic information
- Product Name:
- 2-(1H-Imidazol-1-yl)ethanamine
- Synonyms:
-
- 2-IMIDAZOL-1-YL-ETHYLAMINE DIHYDROCHLORIDE
- 2-Imidazol-1-yl-ethylamine1500
- 1H-Imidazole-1-ethanamine 2HCl
- 1H-Imidazole-1-ethanamine
- N-(2-Aminoethyl)imidazole
- [2-(1H-imidazol-1-yl)ethyl]amine hydrochloride
- 2-(1H-Imidazol-1-yl)ethanamine
- 2-(1H-imidazol-1-yl)ethanamine(SALTDATA: 2HCl)
- CAS:
- 5739-10-6
- MF:
- C5H9N3
- MW:
- 111.15
- Product Categories:
-
- Imidazol&Benzimidazole
- Mol File:
- 5739-10-6.mol
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2-(1H-Imidazol-1-yl)ethanamine Chemical Properties
- Boiling point:
- 283℃
- Density
- 1.15
- Flash point:
- 125℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 7.51±0.10(Predicted)
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2-(1H-Imidazol-1-yl)ethanamine Usage And Synthesis
Uses
2-(1H-Imidazol-1-yl)ethanamine is an intermediate for the preparation of selective tumor inhibitor bis(nitroimidazolyl)alkanecarboxamide hypoxia.
Synthesis
Imidazole (8.10 g, 119 mmol), 2-chloroethylamine monohydrochloride (15.2 g, 131 mmol), tetrabutylammonium hydrogensulfate (1.62 g, 4.8 mmol), and sodium hydroxide (17.1 g, 428 mmol) were combined with 100 ml acetonitrile and heated under reflux for 21 h. The reaction mixture was cooled and filtered. The filtrate was concentrated to a pale yellow oil. Flash chromatography (silica gel, gradient elution of acetonitrile to 9:1 acetonitrile/NH4OH) afforded 4.52 g (34%) of 2-(1H-Imidazol-1-yl)ethanamine as a pale yellow oil.
2-(1H-Imidazol-1-yl)ethanamineSupplier
Shanghai ChangQi Biochemical Technology Co., Ltd. Gold
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2-(1H-Imidazol-1-yl)ethanamine(5739-10-6)Related Product Information
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- N'1-(3-THIENYLMETHYLIDENE)-2-(4,5-DICHLORO-1H-IMIDAZOL-1-YL)ETHANOHYDRAZIDE
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